Cyclohexanone monooxygenase (CHMO)
Tsanangudzo Pfupi
Nezve Cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): a Baeyer Villiger monooxygenase (BVMO) ine cyclohexanone se substrate, inogona oxidize cyclohexanone ku cyclohexanol vachishandisa oksijeni.
Imhando ye flavin inotsamira enzyme.Iyo oxidized flavin inoderedzwa kuita flavin kuburikidza nekutenderera kwekudzikisa coenzyme II (NADPH) kune inotevera oxidation.Naizvozvo, cofactor NADPH inodiwa mukutenderera kweflavin.Kune chete mhando imwe chete yeCHMO enzyme chigadzirwa (Nhamba seES-CHMO101) yakagadziridzwa neSyncoZymes, inogona kushandiswa kuita oxidize cyclohexanone kuita cyclohexanone.
Catalytic reaction type:
Nharembozha/Wechat/WhatsApp: +86-13681683526
E-Maillchen@syncozymes.com
| Enzymes | Product Code | Tsanangudzo |
| Screening Kit (SynKit) | ES-CHMO-101 | seti ye1 Ketoreductases, 1 mg imwe neimwe 1 zvinhu * 1mg / chinhu |
★ High substrate chaiyo.
★ Strong chiral selectivity.
★ Kutendeuka kwepamusoro.
★ Zvishoma ne-zvigadzirwa.
★ Mild reaction conditions.
★ Kuchengetedza zvakatipoteredza.
➢ Kazhinji, maitiro ekuita anofanira kusanganisira substrate, buffer solution, enzyme, coenzyme uye coenzyme regeneration system (eg glucose uye glucose dehydrogenase).
➢ CHMO inofanirwa kuwedzerwa kwekupedzisira mukuita system, mushure mekunge pH uye tembiricha zvagadziriswa kune maitiro ekuita.
Muenzaniso 1(Synthesis ye cyclohexanol kubva ku cyclohexanol)(1):
Chengeta makore maviri pasi -20 ℃.
Usambofa wakasangana nemamiriro akanyanya akadai se: tembiricha yakakwira, yakakwira / yakaderera pH uye yakakwira concentration organic solvent.
1. Friso, Marco, Appl Microbiol Biotechnol, 2017, 101(20): 7557-7565
