-
Transaldolase (TAL)
Nezve Transaldolase
ES-TAL (Transaldolase): inonyanya kureva threonine transaldolases, iyo inogona kukonzera reaction yekugadzira β-hydroxyphenylalanine derivatives ne threonine uye benzaldehyde derivatives. TAL ienzyme inoenderana nePLP. Kune mhando imwe chete yechigadzirwa cheTAL enzyme (Nhamba seES-TAL101) yakagadzirwa neSyncoZymes, iyo inogona kushandiswa kugadzira β-hydroxyphenylalanine uye derivatives yayo.
Rudzi rwekuita kweCatalytic:
Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
-
Ketoreductase (KRED)
Nezve Ketoreductase
MaEnzme: Mapuroteni ndiwo mapuroteni anokonzera mamorekuru, maenzyme mazhinji ndiwo mapuroteni.
Ketoreductase: Inonziwo "Carbonyl reductase", ma enzymes anokonzera reversible redox reaction pakati pealdehydes / ketones uye alcohols, uye anoda coenzymes seH transmitter senge NADH kana NADPH. Kune mapoka matatu makuru eKRED: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), uye Aldo-KetoReductases (AKRs). Mabasa e catalytic evatatu ava akafanana, asi chimiro uye hunhu hwakasiyana zvikuru.
Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
-
Transaminase (ATA)
Nezve transaminase
ATA inobva kuSyncoZymes: Kune mhando makumi matanhatu nematanhatu dzezvigadzirwa zve ATA enzyme (Nhamba seES-ATA-101~ES-ATA-166) yakagadzirwa neSyncoZymes. SZ-ATA chishandiso chinobatsira pakugadzira chiral amines, amino acids nezvimwe zvinobva mumhando dzakasiyana dze aliphatic ne aromatic ketoacids, aldehydes, ketones uye ketoses.
Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
-
Nitrilase (NIT)
NezveNitrilase
ES-NITs: Shandura zvakananga cyanide group kuita carboxyl group, kugadzira carboxylic acid, iyo inoshandiswa zvakanyanya mukurapa, kuchengetedza nharaunda, indasitiri yemakemikari, chinowedzera chikafu, machira, kugadzirwa kwekurima nedzimwe nzvimbo.
Kune mhando makumi mana dzezvigadzirwa zveNitrilase (NIT) (Nhamba seES-NIT-101~ES-NIT-140) zvakagadzirwa neSyncoZymes. ES-NIT chishandiso chinobatsira pakugadzira chiral carboxylic acids kuburikidza ne regio- uye stereoselective hydrolysis yemhando dzakasiyana dze aliphatic ne aromatic nitriles.Rudzi rwekuita kweCatalytic:
Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
-
Nitrile hydratase (NHT)
Nezve ES-NHTs
ES-NHTs: rudzi rwemetalloenzyme, iyo inonyungudutsa nitriles muamide yekutanga inoenderana nayo. Inoshandiswa zvakanyanya kwete chete pakugadzira amino acids, amides, carboxylic acids uye zvinobva mazviri, asiwo pakugadzira mishonga ye chiral. Kune mhando makumi maviri nemana dze nitrile hydratases dzakagadzirwa neSyncoZymes (Nhamba seES-NHT-101～ES-NHT-124).
Rudzi rwekuita kweCatalytic:
Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
-
Amidase (AMD)
AMD kubva kuSyncoZymes: Kune mhando gumi nemapfumbamwe dzezvigadzirwa zve enzyme zve AMD (Nhamba seES-AMD-101~ES-AMD-119) zvakagadzirwa neSyncoZymes. SZ-AMD chishandiso chinobatsira chekusimudzira kugadzirwa kwe chiral carboxylic acids uye zvinobuda mazviri kubva mumhando dzakasiyana dze aliphatic ne aromatic amides.
Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
-
Ene reductase (ERED)
Nezve ene reductase
ES-EREDs: Ndeyemhuri yema enzymes ekare eyero anoderedza C=C mu α, β-unsaturated compounds ane ma electron-absorbing groups. Anoshandiswa zvakanyanya mukudzidza nezve amino acid derivatives, bioactive substances, pharmaceutical intermediates, spices uye chiral blocks.
Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
-
MaOxynitrilases (HNL)
Nezve oxynitrilases
ES-HNLs: Iyi enzyme yekirasi inosanganisa kuwedzera kweHCN mu aldehydes (ketones) kuti iwane R kana S type cyanide alcohols, iyo inogona kushandurwa nyore nyore kuita mhando dzakawanda dzemishonga kana mishonga inopindirana kuburikidza nenzira yemakemikari.
Kune mhando makumi maviri nemapfumbamwe dzezvigadzirwa zve oxynitrilase (Nhamba seES-HNL-101～ES-HNL-129) zvakagadzirwa neSyncoZymes. SZ-HNL chishandiso chinobatsira pakugadzira (R)-cyanohydrins kana (S)-cyanohydrins kubva mumhando dzakasiyana dzearomatic, aliphatic uye heterocyclic aldehydes kana kunyange ketones.
Rudzi rwekuita kweCatalytic:
Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
-
Nitro reductase (NTR)
Nezve nitro reductase
ES-NTRs: Ndiwo ma flavoenzymes anokonzera kudzikiswa kweNAD(P)H kwema nitro groups pa nitroaromatic ne nitroheterocyclic compounds kuita hydroxylamino uye/kana amino derivatives. Anoshandiswa zvakanyanya mukugadzirwa kwe aromatic hydroxylamine ne aromatic amine, kurapwa ne tumor, kuona biological uye kuparadza tsvina yezvakatipoteredza. Kune mhando gumi nembiri dzeNitro reductase (NTR) products (Nhamba seES-NTR-101~ES-NTR-112) yakagadzirwa neSyncoZymes.
Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
-
Aldolase (DERA)
ES-DERA: Inogona kumutsa zvinobudirira kuwedzera ma ketone evanopa kune ma receptor aldehydes. Uyezve, mhinduro yacho inogona kuitwa mumvura ine pH isina kusimba pasina matanho akakosha ekudzivirira. Ndee class I aldolase, iyo inoumba Shiff base mu catalytic process. Substrate iyi yakabatana ne amino group yenzvimbo inoshanda kuti itange kutyoka uye kuumbwa kwechisungo. Musiyano uripo pakati peDERA nedzimwe aldolases ndewekuti substrates dzavanomutsa i aldehydes uye dzinogona kunyura mu continuous aldehydes condensation.
Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
-
Cytochrome P450 monooxygenase (CYP)
NezveCYP
ES-CYPs: Rudzi rwema enzymes e redox ane mercaptan-heme senzvimbo inoshanda yekufambisa okisijeni. Aya ndiwo ma terminal oxygenases uye anoda heme kuti aite kuti okisijeni ishande.
Cytochrome P450 monooxygenase inokonzeresa oxidation, epoxidation uye hydroxylation yealkyl, hydroxylation uye oxidation yeammonia, oxidation yesarufa, dealkylation (oxygen, sarufa, ammonia), oxidative dehydrogenation, deamination uye dehalogenation.
Kune mhando sere dzezvigadzirwa zve cytochrome P450 monooxygenase (Nhamba seES-CYP-101～ES-CYP-108) zvakagadzirwa neSyncoZymes.Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
-
Doro rinopisa (AOX)
Nezve alcohol oxidase
ES-AOXs: Ma enzyme aya anokwanisa kukonzera oxidation yemafuta alcohols kana aryl-alcohols kuti igadzire aldehydes. Anoshandisa molecular oxygen asi haadi cofactor yakawedzerwa kunze, uye hydrogen peroxide inogadzirwa.
Kune mhando nhanhatu dzezvigadzirwa zvealcohol oxidases (Nhamba seES-AOX-101~ES-AOX-106) zvakagadzirwa neSyncoZymes. ES-AOX101 neES-AOX102 dzinoda substrates dzealcohol dzakagadzirwa nealiphatic, ES-AOX103~ ES-AOX105 dzinoda substrates dzealcohol dzine aromatic, uye ES-AOX106 icholesterol oxidase. SZ-AOX chishandiso chinobatsira pakugadzira oxidation yemafuta ane alcohols kana aryl-alcohols kuti igadzire aldehydes.
Rudzi rwekuita kweCatalytic:
Nharembozha/Wechat/WhatsApp: +86-13681683526
Tsamba yemagetsi:lchen@syncozymes.com
