SyncoZymes

zvigadzirwa

Cytochrome P450 monooxygenase (CYP)

Tsanangudzo Pfupi

Nezve CYP

ES-CYPs: Kirasi redox enzymes ine mercaptan-heme senzvimbo inoshanda yekukonzeresa kutamisa okisijeni.Iwo materminal oxygenases uye anoda heme kuti aite okisijeni.

Cytochrome P450 monooxygenase catalyze the oxidation, epoxidation uye hydroxylation yealkyl, hydroxylation uye oxidation yeammonia, oxidation yesarufa, dealkylation (oxygen, sulfur, ammonia), oxidative dehydrogenation, deamination uye dehalogenation.
Kune 8 mhando dze cytochrome P450 monooxygenase zvigadzirwa (Nhamba seES-CYP-101~ES-CYP-108) yakagadzirwa neSyncoZymes.

Nharembozha/Wechat/WhatsApp: +86-13681683526

E-Maillchen@syncozymes.com


Product Detail

Product Tags

Nezve CYP:

Catalytic reaction type:

cyp
cyp1
cyp2

Product Information:

cyp3
Enzymes Screening Kit (SynKit) Tsanangudzo
Enzyme Powder ES-CYP-101~ ES-CYP-108 seti ye8 Cytochrome P450 Monooxygenases, 50 mg imwe neimwe 8 zvinhu * 50mg / chinhu, kana humwe huwandu
Screening Kit (SynKit) ES-CYP-800 seti ye8 Cytochrome P450 Monooxygenases, 1mg chimwe nechimwe 8 zvinhu * 1mg / chinhu

Zvakanakira:

★ Broad substrate spectrum.
★ Kutendeuka kwepamusoro.
★ Zvishoma ne-zvigadzirwa.
★ Mild reaction conditions.
★ Kuchengetedza zvakatipoteredza.

Mirayiridzo yekushandisa:

➢ Kazhinji, maitiro ekugadzirisa anofanirwa kusanganisira substrate, buffer solution (Iyo optimum reaction pH ye enzyme), coenzyme (NAD (H) kana NADP (H)), coenzyme regeneration system (eg glucose uye glucose dehydrogenase) uye ES-CYP.coenzyme uye coenzyme regeneration system inogona kutsiviwa nehydrogen peroxide mune chikamu chekuita system.
➢ Mhando dzese dzeES-CYP dzinoenderana neakasiyana optimum reaction mamiriro anofanirwa kudzidzwa ega.
➢ High concentration yeSubstrate kana chigadzirwa chine chinogona kutadzisa kuita kweES-CYP.Nekudaro, iyo inhibition inogona kudzikiswa nebatch kuwedzera kwe substrate.

Mienzaniso Yekushandisa:

Muenzaniso 1(1):

cpyExample1

Muenzaniso 2(2):

cpyExample2

Muenzaniso 3(3):

cpyExample3

Muenzaniso 4(4):

cpyExample4

Kuchengeta:

Chengeta makore maviri pasi -20 ℃.

Chenjerera:

Usambofa wakasangana nemamiriro akanyanya akadai se: tembiricha yakakwira, yakakwira / yakaderera pH uye yakakwira concentration organic solvent.

References:

1. Zaretzki J, Matlock M, uye Swamidass S JJ Chem.Inf.Muenzaniso, 2013, 53, 3373-3383.
2. Gannett P M., Kabulski J, Perez F A., e tal.J. Am.Chem.Soc., 2006, 128 (26), 8374–8375.
3. Cryle M J., Matovic N J., uye De Voss J J. Org.Lett., 2003, 5 (18), 3341–3344.
4. Kawauchi, H., Sasaki, J., Adachi, T., e tal.Biochim.Biophys.Acta, 1994, 1219, 179.
5. Yasutake, Y., Fujii, Y.;Cheon, WK e tal.Acta Crystallog.2009, 65, 372.


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