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Nucloside phosphorylse (NP)
Nezve nucleoside phosphorylse
Kune mhando nhatu dzezvigadzirwa zve NP enzyme (Nhamba se ES-NP-101~ ES-NP-103) zvakagadzirwa neSyncoZymes. ES-NP-101 ipurine nucleoside phosphorylase, ES-NP-102 uye ES-NP-103 ipyrimidine nucleoside phosphorylase. Nucleosidephosphorylase inogona kuputsa nucleosides kuita mabhesi uye pentose phosphate. Nucleoside phosphorylase inogona kukamurwa kuita purine nucleoside phosphorylase uye pyrimidine nucleoside phosphorylase zvichienderana nezvinodiwa ne nucleoside bases. Purine nucleoside phosphorylase inogona kusanganisa adenosine ne adenine, inosine ne hypoxanthine, guanosine ne guanine, uye kugadzira ribose phosphate panguva imwe chete. Pyrimidine nucleoside phosphorylase inogona kusanganisa uridine ne uracil uye kugadzira ribose phosphate.
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Hydroaminase (HAM)
Nezve Hydroaminase
Kune mhando mbiri dzechinhu chinogadzirwa neHAM enzyme (Nhamba seES-HAM-101~ ES-HAM-102) chakagadzirwa neSyncoZymes. HAM inogona kukonzera ammonia yeenoic acid kana zvinobva mairi kuti igadzire chiral amino acids. HAM inogona kushandiswa kugadzira chiral amino acids (kana chiral amines) kubva kuenoic acids (kana alkenes). Ammonia donor, senge ammonia water kana ammonium salt, inodiwa.
Hydroaminase catalytic reaction rudzi
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CALB Isina Kufamba
CALB
Recombinant Lipase B inobva kuCandida antarctica (CALB) inogadzirwa nekuvirisa mumvura nePichia pastoris yakagadziriswa majini.
CALB inogona kushandiswa muchikamu chemvura kana chikamu cheorganic catalytic esterification, esterosis, transesterification, ring opening polyester synthesis, aminolysis, hydrolysis yeamides, acylation yeamines uye addition reaction.
CALB ine chiral selectivity yakanyanya uye chinzvimbo selectivity, saka inogona kushandiswa zvakanyanya mukugadzira mafuta, chikafu, mishonga, cosmetic uye mamwe maindasitiri emakemikari.
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NADH oxidase (NOX)
Nezve NADH oxidase
ES-NOX (NADH oxidase): NOX inokonzeresa oxidation yeNADH kuenda kuNAD+, uye ndeye oxidoreductase. Mukuita oxidation, O2 inodiwa se oxidant, uye inoderedzwa kusvika kuH2O kana H2O2. Kune mhando ina dze NOX enzyme products (ES-NOX-101~ES-NOX-104) yakagadzirwa nekambani yedu, iyo inogona kushandiswa pakugadzirisa oxidation ye coenzyme NAD+.
Rudzi rwekuita kweCatalytic:
or
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Phenylalanine ammonia lyase (PAL)
Nezve Phenylalanine ammonia lyase
ES-PAL: Rudzi rwema enzymes anokonzera kubviswa kweL-phenylalanine zvakananga kuita transcinnamic acid. Syncozymes yakagadzira zvinhu gumi zvephenylalanine ammonia lyase (yakaverengerwa ES-PAL-101~ES-PAL-110), izvo zvinogona kushandiswa mukubvisa kana kudzoreredza reverse response yephenylalanine nezvimwe zvinobva mairi.
Rudzi rwekuita kweCatalytic:
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Catalase (CAT)
NezveCatalase
ES-CAT (Catalase): inokonzeresa kuora kweH2O2 kuita okisijeni nemvura. Inonyanya kuwanikwa mumitochondria, endoplasmic reticulum, chiropa chemhuka nemasero matsvuku eropa, kunyanya muchiropa chine huwandu hwakawanda, ichipa basa rekudzivirira muviri kubva pakukuvadza mabhakitiriya. Mubiocatalysis, inonyanya kushandiswa kubvisa reaction by-product hydrogen peroxide uye kuderedza kudziviswa uye kushaikwa kweenzyme nehydrogen peroxide. Kune mhando imwe chete yezvigadzirwa zveCAT enzyme zvakagadzirwa neSyncoZymes (Nhamba seES-CAT).
Rudzi rwekuita kweCatalytic:
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Lysine oxidase (LO)
Nezve Lysine oxidase
ES-LO (Lysine oxidase): inokonzeresa oxidation yeL-lysine kuita 6-amino-2-oxohexanoic acid (kana lactone yayo). Kune mhando imwe chete yechigadzirwa cheLO enzyme (Nhamba seES-LO) yakagadzirwa neSyncoZymes.
Rudzi rwekuita kweCatalytic:
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Phosphokinase (PKase)
Nezve Phosphokinase
ES-PKase (Phosphokinase): inokonzera kutamiswa kwemapoka ephosphate paATP kuenda kune mamwe makomponi. Inobatsirawo kutamiswa kwemapoka ephosphate pane mamwe ma nucleoside etriphosphate dzimwe nguva. Mazhinji ma kinases anoda divalent metal ions kuti atore chikamu mu reaction (kazhinji Mg2+). Kune mhando makumi maviri nerimwe dzePKase enzyme products (Nhamba seES-PKase101~ ES-PKase-121) yakagadzirwa neSyncoZymes.
Rudzi rwekuita kweCatalytic:
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Cyclooxygenase (COX)
Nezve Cyclooxygenase
ES-COX (Cyclooxygenase): inokonzeresa kushandurwa kweC=C bonds kuita epoxide. Kune mhando gumi neimwe dzeCOX enzyme products (Nhamba seES-COX101~ ES-COX-111) yakagadzirwa neSyncoZymes. Zvichienderana nemaitiro akasiyana e catalytic, COX yeSyncoZymes yakakamurwa kuita haloperoxidase ne styrene monooxygenase. ES-COX101, 102, 107-111 ndeye haloperoxidase, nepo ES-COX103-106 iri ye styrene monooxygenase.
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Cyclohexanone monooxygenase (CHMO)
Nezve Cyclohexanone monooxygenase
ES-CHMO (Cyclohexanone monooxygenase): Baeyer Villiger monooxygenase (BVMO) ine cyclohexanone se substrate, inogona kuoxidize cyclohexanone kuita cyclohexanol ichishandisa oxygen.
Imhando yeenzyme inoenderana neflavin. Flavin yakasanganiswa inoderedzwa kuita flavin kuburikidza nedanho rekuderedza coenzyme II (NADPH) kune oxidation inotevera. Nokudaro, cofactor NADPH inodiwa mudenderedzwa reflavin. Kune mhando imwe chete ye CHMO enzyme product (Nhamba seES-CHMO101) yakagadzirwa neSyncoZymes, iyo inogona kushandiswa kuoxidation cyclohexanone kuita cyclohexanone.
Rudzi rwekuita kweCatalytic:
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Carboxylic acid reductase (CAR)
Nezve Carboxylic acid reductase
ES-CAR (Carboxylic acid reductase): inokonzeresa kudzikiswa kweboka re carboxyl kuita boka re aldehyde. Mukuita kwe catalytic, ATP activation uye coenzyme NADPH zvinodiwa se hydrogen transporters. Kune mhando mbiri dze CAR enzyme products (Nhamba se ES-CAR101~ ES-CAR-102) yakagadzirwa neSyncoZymes.
Rudzi rwekuita kweCatalytic:
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Phenylalanine dehydrogenase (PDH)
Nezve Phenylalanine dehydrogenase
ES-PDH: Rudzi rweoxidoreductase. Mhinduro yakanaka inogona kukonzera deamination yeL phenylalanine munyu kana paine NAD kuti igadzire phenylpyruvate munyu, uye reverse reaction inogona kukonzera kugadzirwa kweamino acid munyu unoenderana ne phenylpyruvate munyu. Syncozymes yakagadzira zvinhu zvisere zve phenylalanine dehydrogenase (yakaverengwa ES-PDH-101~ES-PDH-108). ES-PDH inogona kushandiswa kugadzira phenylalanine munyu kana amino acid munyu unoenderana ne phenylpyruvic acid munyu kana derivatives.
Rudzi rwekuita kweCatalytic:
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