Triglyceride (TG) rudzi rwemafuta ane huwandu hwakawanda mumuviri wemunhu. Nhengo dzese dzemuviri wemunhu dzinogona kushandisa triglyceride kupa simba, uye chiropa chinogona kugadzira triglyceride uye kuchichengeta muchiropa. Kana triglyceride ikawedzera, zvinoreva kuti chiropa chinounganidza mafuta akawandisa, anova chiropa chine mafuta. Triglyceride rudzi rwehyperlipidemia, uye kukuvadza kwayo kukuru mumuviri wemunhu ndiko kukonzera atherosclerosis, kuvharika kwetsinga dzeropa uye thrombosis. Pamusoro pezvo, zvidzidzo zvakaratidza kuti triglycerides yakakwira inogona zvakare kukonzera BP, matombo emunduru, pancreatitis, chirwere cheAlzheimer nezvimwewo.
Ongororo yekiriniki yevanhu ichangobva kuitwa muJapan yakaratidza zvakare mabhenefiti eNMN kumuviri wemunhu. Kuburikidza nemiedzo yekiriniki yevanhu, timu yekutsvagisa yakaratidza kuti kubaiwa kweNMN netsinga kwakachengeteka mumuviri wemunhu, izvo zvisingangogone kuwedzera huwandu hweNAD+ muropa chete, asiwo kuderedza zvakanyanya huwandu hwetriglyceride muropa pasina kukuvadza masero eropa.
Chikwata chekutsvagisa chakatora vanhu gumi vane hutano hwakanaka (varume vashanu nevakadzi vashanu, vane makore 20 kusvika 70). Mushure mekutsanya kwemaawa gumi nemaviri, 300mg yeNMN yakanyungudutswa mu100mL saline ndokubayiwa muvanhu vakazvidira kuburikidza netsinga yeruoko (5mL/min). MaX-ray epachipfuva akatorwa vasati vabayiwa jekiseni reNMN uye mushure mekubayiwa, uye huremu, tembiricha, BP, pulse uye oxygen saturation yeropa zvakayerwa. Ropa neweti zvakaunganidzwa kuti zviongororwe. Kuburikidza nekuenzanisa mhedzisiro yebvunzo dzakawanda, zvakaonekwa kuti zviratidzo zvikuru zvechiropa, pancreas, moyo neitsvo hazvina shanduko dziri pachena, uye pamusoro pezvo, hazvizokanganisi zviratidzo zvikuru zvemasero matsvuku eropa, masero machena eropa uye maplatelet muropa, uye vatori vechikamu havana maitiro akaipa.
Zvakakosha kuziva kuti huwandu hwe triglyceride muropa hwakachinja zviri pachena. Mushure mekunge vanhu vapihwa jekiseni reNMN kwehafu yeawa, huwandu hwe triglyceride hwakadzikira zviri pachena, kusvika maawa mashanu gare gare, kunyangwe paine mafambiro ekupora zvishoma, musiyano uyu wakakosha wakaramba uripo.
Kubva pakuedza mhuka dzisati dzaongororwa kusvika pakuedza kwevanhu, mabhenefiti eNMN kumuviri wemunhu akasimbiswa zvinobudirira. Chidzidzo ichi chekurapa kwevanhu chinoratidza kushanda kweNMN mukuderedza triglyceride, inova nhau dzakanaka kune vanhu vakafuta uye vakwegura.
Mareferensi:
[1]. Kimura S, Ichikawa M, Sugawara S, nevamwe. (Gunyana 05, 2022) Nicotinamide Mononucleotide Inogadziriswa Zvisina Kukuvadzwa uye Inoderedza Zvikuru Mazinga eTriglyceride muRopa muVanhu Vane Hutano. Cureus 14(9): e28812. doi:10.7759/cureus.28812
Nguva yekutumira: Mbudzi-11-2022