Triglyceride (TG) imhando yemafuta ane yakakura zvirimo mumuviri wemunhu.Nhengo dzese uye matishu emuviri wemunhu anogona kushandisa triglyceride kupa simba, uye chiropa chinogona kugadzira triglyceride nekuichengeta muchiropa.Kana iyo triglyceride ichiwedzerwa, zvinoreva kuti chiropa chinounganidza mafuta akawandisa, ayo ane mafuta echiropa.Triglyceride imhando ye hyperlipidemia, uye kukuvadza kwayo kukuru kumuviri wemunhu ndiko kukonzera atherosclerosis, kuvharika kwetsinga yeropa uye thrombosis.Mukuwedzera, zvidzidzo zvakaratidza kuti high triglycerides inogonawo kukonzera hypertension, gallstones, pancreatitis, chirwere cheAlzheimer uye zvichingodaro.
Ongororo yemazuva ano yekiriniki yevanhu muJapan yakaratidza zvakare mabhenefiti eNMN kumuviri wemunhu.Kuburikidza nemiedzo yekiriniki yevanhu, timu yekutsvagisa yakaratidza kuti jekiseni remukati reNMN rakachengeteka kumuviri wemunhu, izvo zvisingangogone kuwedzera zvakanyanya ropa reNAD + nhanho, asi zvakare kuderedza zvakanyanya mwero weropa wetriglyceride pasina kukuvadza maseru eropa.
Boka rekutsvagisa rakatora vazvipiri vane hutano gumi (5 varume ne5 vakadzi, vane makore makumi maviri ~ 70 makore).Mushure mekutsanya kwemaawa gumi nemaviri, 300mg yeNMN yakanyungudutswa mu 100mL saline uye jekiseni mune vanozvipira kuburikidza neruoko mutsinga (5mL/min).Chest X-rays yakatorwa pamberi uye mushure meNMN jekiseni, uye uremu, tembiricha, BP, pulse uye ropa oxygen saturation zvakayerwa.Ropa neweti zvakaunganidzwa kuti zviongororwe.Kuburikidza nekuenzanisa kuongororwa kwehuwandu hwemhedzisiro yebvunzo, zvinoonekwa kuti mamaki makuru echiropa, pancreas, moyo neitsvo hazvina shanduko dziri pachena, uye nekuwedzera, hazvizokanganisa mamaki makuru emasero matsvuku eropa, masero machena eropa. uye maplatelet muropa, uye vatori vechikamu havana maitiro asina kunaka.
Zvakakosha kuziva kuti chiyero che triglyceride muropa chakashanduka zviri pachena.Mushure mokunge vanhu vakagamuchira jekiseni reNMN kwehafu yeawa, chiyero che triglyceride chakadonha pachena, kusvikira maawa 5 gare gare, kunyange zvazvo paiva nekatsika kadiki kekugadzirisa, kusiyana kukuru uku kuchiripo.
Kubva pakuedza kwemhuka kwekutanga kusvika kuongororo yekiriniki yevanhu, mabhenefiti eNMN kumuviri wemunhu akave akasimbiswa.Ichi chidzidzo chekiriniki chevanhu chinoratidza basa reNMN mukuderedza triglyceride, inova nhau dzakanaka kune vakafutisa uye vachembera.
References:
[1].Kimura S, Ichikawa M, Sugawara S, et al.(Gunyana 05, 2022) Nicotinamide Mononucleotide Yakanyatsogadziriswa uye Inoderedza Zvinonyanya Ropa Triglyceride Level muvanhu Vane Hutano.Cureus 14(9): e28812.doi:10.7759/cureus.28812
Nguva yekutumira: Nov-11-2022