β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
SyncoZymes (Shanghai) Co., Ltd. ndiyo inotungamira mugadziri uye mutengesi we β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS: 53-59-8) ine mhando yepamusoro.Isu tinogona kupa COA, kuendesa pasi rese, zvidiki uye huwandu hwakawanda huripo.Kana iwe uchifarira chigadzirwa ichi, ndapota tumira ruzivo rwakadzama runosanganisira nhamba yeCAS, zita rechigadzirwa, huwandu kwatiri.Ndokumbira ubate:lchen@syncozymes.com
| Chemical Name | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Mashoko anoreva zvakafanana | β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Nhamba yeCAS | 53-59-8 |
| Molecular Weight | 743.41 |
| Molecular Formula | C21H28N7O17P3 |
| EINECS Nha. | 200-178-1 |
| kuchengetedza temp. | Ramba uri munzvimbo ine rima, Inert atmosphere, Chengetedza mufiriza, pasi pe -20°C |
| solubility | H2O: 50 mg/mL, yakajeka, yero zvishoma |
| pka | pKa1 3.9;pKa2 6.1(pa25℃) |
| λmax | 260nm (lit.) |
| Merck | 14,6348 |
| EPA Substance Registry System | Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester ine 3-(aminocarbonyl) -1-.beta.-D-ribofuranosylpyridinium, munyu wemukati (53-59- 8) |
| Test Item | Zvinotsanangurwa |
| Chitarisiko | Muchena kusvika kuhupfu yeyero |
| Solubility | 200mg/ml mumvura |
| pH kukosha (100mg/ml) | 5.0～7.0 |
| UV Spectral Analysis t 260 nm uye pH 7.5 | (18±1.0)×10³L/mol/cm |
| Zvemukati (nekuongorora enzymatic naG6PDH pa pH 7.5, uchishandisa spectrophotometer, abs.340nm, pane anhydrous basis) | ≥90.0% |
| Kuchena (neHPLC, % nzvimbo) | ≥95.0% |
| Zvemumvura (neKF) | ≤5% |
Package:Bhodhoro, Aluminium foil bag, 25kg/Cardboard Drum, kana zvinoenderana nezvinodiwa nemutengi.
Storage Condition:Ramba wakanyatsomira murima, kuitira kuchengetedza kwenguva refu gara pa2 ~ 8 ℃.
NADP is a coenzyme, inova chinhu umo nicotinamide adenine dinucleotide uye phosphate molecule inosungwa ne ester bond, uye inowanikwa zvakanyanya.munyika yebiology.Yayo makemikari zvimiro, absorption spectrum, redox fomu, nezvimwe zvakafanana neNAD (Coenzyme I).NADP inogona kushandiswa zvakanyanya mukuitainogadziriswa neakasiyana siyana doro dehydrogenases, ketoreductases uye mamwe oxidoreductases.Zvakadai se: inogona kuderedzwa kuNADPH nevakawanda dehydrogenases vakadarose 6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44).Zvisinei, hazvibviri kukwanisa kuita nevakawandadehydrogenases anoshandisa NAD, uye haigone kuve yakananga oxidized neketani yekufema.Kusiyana neNAD, inowanikwa zvakanyanya munzvimbo yakaderedzwa mumaseru ezvipenyu zveaerobic.
Zvinoenderana nekushandiswa kwechigadzirwa, inogona kukamurwa kuita anotevera mamakisi: biotransformation giredhi, diagnostic reagent giredhi, hutano chikafu giredhi.
Biotransformation giredhi: Inogona kushandiswa kugadzirwa kwemishonga yepakati uye APIs, kunyanya ine catalytic enzymes, senge ketoreductase (KRED),P450 monooxygenase (CYP), formate dehydrogenase (FDH), glucose dehydrogenase (GDH), etc. Mira.
Diagnostic reagent giredhi: Iine akasiyana siyana ekuongorora enzymes, seyakagadzirwa zvinhu zvekuongorora kits.
Chikafu chehutano giredhi: Chikafu chekuwedzera chekushandisa cheNADP chiri kunyanya mukutsvaga nekusimudzira maitiro.
