β-Nicotinamide Mononucleotide (NMN)
Munguva pfupi yapfuura, kune nhau dzakanaka mumunda weNMN - mushure mekuongororwa kwakasimba nekomiti yehunyanzvi yesangano rine simba reUS Food and Drug Administration (FDA), zvinhu zveNMN zveShangke Biopharmaceutical (Shanghai) Co., Ltd. (zvino zvichinzi "Shangke Bio") zvatenderwa neUnited States. Kubvumidzwa kweFDA NDI kunosimbisa kuti zvinhu zvayo zveNMN zvinogona kushandiswa zviri pamutemo mukugadzira, kutengesa uye kukwidziridzwa kwezvekudya zvinovaka muviri muUnited States, uye zvinogona kuwanikwa pawebhusaiti yepamutemo yeFDA sezvinhu zvitsva zvezvekudya zvinovaka muviri, nhamba 1247.
FDA NDI ndiyo nzira inonyanya kukosha yekupa zvitupa mumusika weUS. Kuwana chitupa ichi hakurevi chete kuti kuchengetedzeka uye mhando yezvigadzirwa zveShangke Bio zviriinozivikanwa zvikuru, asi inobatsirawo kuti indasitiri yeNMN irambe ichikura zvakanaka kwenguva refu.
| Zita reKemikari | β-Nicotinamide Mononucleotide |
| Mazwi anoreva zvakafanana | NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSID 5'-PHOSPHATE |
| Nhamba yeCAS | 1094-61-7 |
| Kurema kweMorekuru | 334.22 |
| Fomura yeMolecular | C11H15N2O8P |
| EINECS 号: | 214-136-5 |
| Nzvimbo yekunyunguduka | 166 °C (Zvita) |
| tembiricha yekuchengetedza. | -20°C |
| kunyungudika | DMSO (Inopisa zvishoma), Methanol (Zvishoma), Mvura (Zvishoma) |
| chimiro | Yakasimba |
| ruvara | Chena kusvika Yero |
| Merck | 13,6697 |
| BRN | 3570187 |
| Kugadzikana: | Zvakanyanya Kupenya |
| InChIKey | DAYLJWODMCOQEW-TURQNECASA-N |
| Chinhu Chekuyedza | Magadzirirwo |
| Chitarisiko | Upfu hwekristalline hunobva pachena kusvika pakachena |
| Zvakawanda zveSodium | ≤1% |
| kukosha kwepH (100mg/ml) | 2.0~4.0 |
| Kuchena | ≥99.0% |
| Mvura iri mukati | ≤1% |
| Simbi dzinorema | <10ppm |
| Arsenic | <0.5ppm |
| Tungamira | <0.5ppm |
| Mercury | <0.1ppm |
| Cadmium | <0.5ppm |
| Zvisaririra zve solvent | Ethanol≤1000ppm |
| Huwandu Hwese hweMabhakitiriya Anofamba Nemhepo | <750cfu/g |
| Mbiriso & Mould | <25cfu/g |
| Makorifomu ese | ≤0.92MPN/g |
| E. Coli | Zvakaipa |
| Salmonella | Zvakaipa |
| Staph. Aureus | Zvakaipa |
| Kuyedza (kuburikidza ne anhydrous basis) | ≥99.0% |
| Mwero wekudzika | ≥95% |
| Kuwanda kwehuwandu | Taura nezveruzivo |
Pasuru:Bhodhoro, bhegi refoiri reAruminiyamu, 25kg/Cardboard Drum, kana zvichienderana nezvinodiwa nemutengi.
Mamiriro Ekuchengetedza:Chengeta mumidziyo yakasimba, isingatsvedzerere, kuti igare kwenguva refu ichichengetwa pa2~8°C kana pasi.
Nicotinamide Mononucleotide (NMN) ivhitamini B3 itsva inova nhanho imwe chete yekutanga NAD+ (Nicotinamide Adenine Dinucleotide). NMN ndiyo yekutanga NAD+ restorer yemasero yakaratidzwa kuti inoshanda pakudzoreredza masero mumuviri.
Nicotinamide Adenine Dinucleotide (NAD) ndeimwe yemamorekuru akakosha uye anonakidza mumuviri. Inodiwa kune anopfuura mazana mashanu emakemikari anoita basa guru mukutonga kwemaitiro ese makuru ehupenyu (Ansari naRaghava, 2010). Pamusoro pezvose, inogona kutibvumira kurarama hupenyu hune hutano uye hwakareba.
Nicotinamide Adenine Dinucleotide (NAD) inowanikwa muchimiro chayo cheoxidized (NAD+) kana muchimiro chakaderedzwa (NADH), izvo zviri zvinhu zvakakosha zvemaoxireductases akawanda.
SyncoZyems ndiyo kambani yekutanga kuwana kambani yekugadzira zvinhu zvakabikwa yakatenderwa neFDA NDI NMN, inomiririra mukuru weFDA anogamuchira NMN semhando itsva yezvinhu inogona kutanga kugamuchirwa uye kutenderwa sezvinhu zvekudya zvinowedzera muUnited States.
