Cyclooxygenase (COX)

Tsananguro pfupi:

Nezve Cyclooxygenase

ES-COX (Cyclooxygenase): inokonzeresa kushandurwa kweC=C bonds kuita epoxide. Kune mhando gumi neimwe dzeCOX enzyme products (Nhamba seES-COX101~ ES-COX-111) yakagadzirwa neSyncoZymes. Zvichienderana nemaitiro akasiyana e catalytic, COX yeSyncoZymes yakakamurwa kuita haloperoxidase ne styrene monooxygenase. ES-COX101, 102, 107-111 ndeye haloperoxidase, nepo ES-COX103-106 iri ye styrene monooxygenase.

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Tsamba yemagetsi:lchen@syncozymes.com

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Ruzivo rweChigadzirwa

Matagi eChigadzirwa

Nezve Cyclooxygenase:

Rudzi rwekuita kweCatalytic:

Haloperoxidase:

Styrene monooxygenase:

Ruzivo rweChigadzirwa:

MaEnzayimu	Kodhi Yechigadzirwa	Tsanangudzo
Upfu hweEnzimu	ES-COX-101~ ES-COX-110	seti ye10 NADH Cyclooxygenase, 50 mg chimwe nechimwe 10 zvinhu * 50mg / chinhu, kana chimwe chiyero

Zvakanakira:

★ Hunhu hwepamusoro hwe substrate.
★ Kusarudza kwakasimba kwerudo rwechikara.
★ Kuchinja kwakanyanya.
★ Zvibereko zvishoma.
★ Mamiriro ekuita zvinhu zvisina kusimba.
★ Inochengetedza zvakatipoteredza.

Mirayiridzo yekushandisa:

➢ Kazhinji, haloperoxidase reaction system inosanganisira: substrate, buffer, enzyme, H2O2 uye halogen ion. Styrene monooxygenase reaction system inosanganisira substrate, buffer, enzyme, coenzyme uye coenzyme regeneration system
➢ COX inofanira kuwedzerwa pakupedzisira mu reaction system, mushure mekunge pH netembiricha zvagadziriswa kuti zvienderane nemamiriro e reaction.

Mienzaniso yeMashandisirwo:

Muenzaniso 1 (Kugadzirwa kwezvinhu zvinogadzirwa ne epoxy styrene kubva kune zvinogadzirwa ne styrene)⁽¹⁾:

Cherechedza: mienzaniso yekushandisa uye mareferensi akagadzirirwa kuratidza huwandu hwekushandiswa kweCOX kuti zvive nyore kunzwisisa, uye hazvienderane neenzyme chaiyo yeSyncoZymes.