Ketoreductase (KRED)
KRED kubva SyncoZymes: Kune zana nemakumi mapfumbamwe nerimwe emhando dzeKRED enzyme zvigadzirwa (Nhamba seES-KRED-101~ES-KRED-291) yakagadziriswa neSyncoZymes.SZ-KRED inogona kushandiswa zvakanyanya mu regio- uye stereoelective kuderedza aldehydes, beta-ketone esters, α-ketone esters uye ketone.
Catalytic reaction type:
| Enzymes | Product Code | Tsanangudzo |
| Enzyme Powder | Enzyme Powder | seti ye187 Ketoreductases, 50 mg imwe neimwe 187 zvinhu * 50mg / chinhu, kana humwe huwandu |
| Screening Kit (SynKit) | ES-KRED-18100 | seti ye181 Ketoreductases, 1 mg imwe neimwe 181 zvinhu * 1mg / chinhu |
★ High substrate chaiyo.
★ Strong chiral selectivity.
★ High kutendeuka kushanda zvakanaka.
★ Zvishoma ne-zvigadzirwa.
★ Mild reaction conditions.
★ Kuchengetedza zvakatipoteredza.
➢ Kuongororwa kwe enzyme kunofanirwa kuitirwa kune chaiwo ma substrate nekuda kweiyo substrate chaiyo, uye kuwana enzyme inokonzeresa iyo yakanangwa substrate ine yakanakisa catalytic mhedzisiro.
➢ Usambofa wakabata nemamiriro akanyanya akadai se: tembiricha yepamusoro, yakakwirira/yakaderera pH uye organic solvent ine yakanyanya kugadzikana.
➢ Kazhinji, maitiro ekugadzirisa anofanirwa kusanganisira substrate, buffer solution, coenzymes (NAD (H) kana NADP (H)), coenzyme regeneration system (eg glucose uye glucose dehydrogenase).
➢ KRED inofanira kuwedzerwa kwekupedzisira mukuita system, mushure mekunge pH uye tembiricha zvagadziriswa kune mamiriro ekuita.
➢ Ese marudzi eKRED ane akasiyana optimum reaction mamiriro, saka imwe neimwe yadzo inofanirwa kuenderera mberi ichidzidzwa yega.
Muenzaniso 1(1):
Muenzaniso 2(2):
1. Li Z, Liu WD, Chen X, e tal.Tetrahedron, 2013, 69, 3561-3564.
2. Ni Y, Li CX, Ma HM, e tal.Appl Microbiol Biotechnol, 2011, 89: 1111-1118.
