Nitrile hydratase (NHT)
Tsanangudzo Pfupi
Pamusoro peES-NHTs
ES-NHTs: kirasi yemetalloenzyme, iyo inosarudza hydrate nitriles mune inoenderana yekutanga amide.Izvo zvakanyanya kushandiswa kwete chete pakugadzirwa kweamino acids, amides, carboxylic acids uye zvinobva kwavari, asiwo pakugadzira chiral zvinodhaka.Kune makumi maviri nemana marudzi e nitrile hydratases akagadzirwa ne SyncoZymes (Nhamba se ES-NHT-101～ES-NHT-124).
Catalytic reaction type:
Nharembozha/Wechat/WhatsApp: +86-13681683526
E-Maillchen@syncozymes.com
| Enzymes | Product Code | Tsanangudzo |
| Enzyme Powder | ES-NHT-101~ ES-NHT-124 | seti ye24 Nitrile Hydratases, 50 mg imwe neimwe 24 zvinhu * 50mg / chinhu, kana humwe huwandu |
| Screening Kit (SynKit) | ES-NHT-2400 | seti ye24 Nnitrile Hydratases, 1 mg imwe neimwe 24 zvinhu * 1mg / chinhu |
★ High substrate chaiyo.
★ Strong chiral selectivity.
★ Kutendeuka kwepamusoro.
★ Zvishoma ne-zvigadzirwa.
★ Mild reaction conditions.
★ Kuchengetedza zvakatipoteredza.
➢ Kazhinji, maitiro ekuita anofanira kusanganisira substrate, buffer solution (optimum reaction pH) uye ES-NHT.
➢ Ese maES-NHT anogona kuyedzwa zvakateerana muhurongwa hwekuita pamusoro kana neNHT Screening Kit (SynKit NHT).
➢ Ese marudzi eES-NHT anoenderana neakasiyana optimum reaction mamiriro anofanirwa kudzidzwa ega.
➢ High concentration yeSubstrate kana chigadzirwa chine chinogona kutadzisa kuita kweES-NHT.Nekudaro, iyo inhibition inogona kurerutswa nebatch yekuwedzera ye substrate, kubatanidza neamidases kana kubviswa kwechigadzirwa.
Muenzaniso 1 (kubatana neamidase)(1):
Muenzaniso 2(2):
Chengeta makore maviri pasi -20 ℃.
Usambofa wakasangana nemamiriro akanyanya akadai se: tembiricha yakakwira, yakakwira / yakaderera pH uye yakakwira concentration organic solvent.
1 Vojtech V, Ludmila M, Alicja BV, uye tal.J Mol Catal B-enzym, 2011, 71: 51-55.
2 Gary W. B, Thomas G, Christopher B. M, na tal.Tetrahedron lett, 2010, 51: 1639-1641.
