Transaldolase (TAL)
Tsanangudzo Pfupi
About Transaldolase
ES-TAL (Transaldolase): inonyanya kureva threonine transaldolases, iyo inogona kukonzera maitiro ekugadzira β-hydroxyphenylalanine derivatives ne threonine uye benzaldehyde derivatives.TAL ndeye PLP inotsamira enzyme.Kune chete mhando imwe chete yeTAL enzyme chigadzirwa (Nhamba seES-TAL101) yakagadziridzwa neSyncoZymes, inogona kushandiswa kugadzira β-hydroxyphenylalanine nezvinobuda mairi.
Catalytic reaction type:
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E-Maillchen@syncozymes.com
★ High substrate chaiyo.
★ Strong chiral selectivity.
★ Kutendeuka kwepamusoro.
★ Zvishoma ne-zvigadzirwa.
★ Mild reaction conditions.
★ Kuchengetedza zvakatipoteredza.
➢ Kazhinji, maitiro ekuita anofanira kusanganisira substrate, buffer solution, enzyme, PLP, Mg2+.
➢ TAL inofanirwa kuwedzerwa kwekupedzisira mukuita system, mushure mekunge pH uye tembiricha zvagadziriswa kune maitiro ekuita.
Muenzaniso 1(Synthesis of (2S, 3R)-p-methylsulfonyl phenylserine kubva p-methylsulfonyl benzaldehyde uye threonine)(1):
Chengeta makore maviri pasi -20 ℃.
Usambofa wakasangana nemamiriro akanyanya akadai se: tembiricha yakakwira, yakakwira / yakaderera pH uye yakakwira concentration organic solvent.
1. CN109836362B
