Imine reductase (IRED)
Tsanangudzo Pfupi
About Imine reductase
ES-IRED: Kirasi yema enzymes anokonzera kuderedzwa kweC = N bond kuCN bond.Iyo ndeye redox enzyme, ine coenzyme NADPH yekutakura hydrogen.Zvinoenderana nezvinodiwa zvechiral zvezvigadzirwa, zvinogona kukamurwa kuita R-IRED uye S-IRED.Syncozymes yakagadzirwa 15 imine reductases (numbIRED ES-IRED-101-ES-IRED-115), iyo inogona kushandiswa zvakanyanya mu regioselective uye stereoelective kuderedza imines kugadzirira chiral amines.
Catalytic reaction type:
Nharembozha/Wechat/WhatsApp: +86-13681683526
E-Maillchen@syncozymes.com
| Enzymes | Product Code | Tsanangudzo |
| Enzyme Powder | ES-IRED-101~ ES-IRED-114 | seti ye14 Imine Reductase, 50 mg imwe neimwe |
| 96-Zvakanaka Enzyme Yekuongorora Kit | ES-IRED-1400 | seti ye14 Imine Reductase, 1 mg imwe neimwe |
★ High substrate chaiyo.
★ Strong chiral selectivity.
★ Kutendeuka kwepamusoro.
★ Zvishoma ne-zvigadzirwa.
★ Mild reaction conditions.
★ Kuchengetedza zvakatipoteredza.
➢ Kazhinji, maitiro ekuita anofanira kusanganisira substrate, buffer solution, enzyme, coenzyme, uye coenzyme regeneration system.
➢ Ese marudzi eES-IRED anoenderana neakasiyana optimum reaction mamiriro anofanirwa kudzidzwa ega.
➢ High concentration yeSubstrate kana chigadzirwa chine chinogona kutadzisa ES-IRED kuita.Nekudaro, iyo inhibition inogona kudzikiswa nebatch kuwedzera kwe substrate.
Muenzaniso 1(Biosynthesis ye chiral 2-methyl pyrrolidine)(1):
Muenzaniso 2(Biosynthesis yechipiri amine)(2):
Muenzaniso 3 (Kuderedzwa kweCyclic Imines)(3):
Chengeta makore maviri pasi -20 ℃.
Usambofa wakasangana nemamiriro akanyanya akadai se: tembiricha yakakwira, yakakwira / yakaderera pH uye yakakwira concentration organic solvent.
1. Scheller PN, Fademrecht S, Hofelzer S, nevamwe.ChemBioChem, 2014, 15, 2201-2204.
2. Wetzl D, Gand M, Ross A, nevamwe.ChemCatChem, 2016, 8, 2023-2026.
3. Li H, Luan ZJ, Zheng GW, nevamwe.Adv.Synth.Catal.2015, 357, 1692-1696.
