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Oxynitrilases (HNL)
Nezve oxynitrilases
ES-HNLs: Enzyme yekirasi iyo inantioselectively inokonzeresa kuwedzera kweHCN kune aldehydes (ketones) kuwana R kana S mhando cyanide alcohols, inogona kushandurwa nyore nyore kuva marudzi mazhinji emishonga kana zvinodhaka zvepakati kuburikidza nemakemikari nzira.
Kune makumi maviri nepfumbamwe emhando dzezvigadzirwa zve oxynitrilase (Nhamba seES-HNL-101～ES-HNL-129) yakagadzirwa neSyncoZymes.SZ-HNL chishandiso chinobatsira kune regio- uye stereo- selective synthesis ye (R) -cyanohydrins kana (S) -cyanohydrins kubva kune zvakasiyana-siyana zvinonhuhwirira, aliphatic uye heterocyclic aldehydes kana kunyange ketoni.
Catalytic reaction type:
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E-Maillchen@syncozymes.com
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Nitro reductase (NTR)
Nezve nitro reductase
ES-NTRs: Maflavoenzymes anokonzera kuderedzwa kweNAD (P) H-inotsamira kwemapoka e nitro pane nitroaromatic uye nitroheterocyclic makomisheni kune hydroxylamino uye/kana amino derivatives.Iwo anoshandiswa zvakanyanya muorganic synthesis yeanonhuwirira hydroxylamine uye anonhuwirira amine, bundu kurapa, kucherechedzwa kwebiological uye kushatisa kwezvakatipoteredza zvinosvibisa.Kune marudzi gumi nemaviri eNitro reductase (NTR) zvigadzirwa (Nhamba seES-NTR-101~ES-NTR-112) yakagadzirwa neSyncoZymes.
Nharembozha/Wechat/WhatsApp: +86-13681683526
E-Maillchen@syncozymes.com
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Aldolase (DERA)
ES-DERAs: Inogona kunyatso gadzirisa iyo stereoselective yekuwedzera yevanopa ketoni kune receptor aldehydes.Uyezve, maitiro anogona kuitwa mune aqueous solution yearere pH pasina akakosha ekudzivirira matanho.Ivo ndevekirasi I aldolase, iyo inoumba Shiff base mune inokonzeresa maitiro.Iyo substrate inosungirirwa zvakabatana neboka reamino renzvimbo inoshanda kuti itange kuparara uye kuumbwa kwechisungo.Musiyano uripo pakati peDERA nemamwe maaldolases ndewekuti masubstrates avanokonzeresa maaldehydes uye anogona kuenderera mberi aldehydes condensation.
Nharembozha/Wechat/WhatsApp: +86-13681683526
E-Maillchen@syncozymes.com
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Cytochrome P450 monooxygenase (CYP)
Nezve CYP
ES-CYPs: Kirasi redox enzymes ine mercaptan-heme senzvimbo inoshanda yekukonzeresa kutamisa okisijeni.Iwo materminal oxygenases uye anoda heme kuti aite okisijeni.
Cytochrome P450 monooxygenase catalyze the oxidation, epoxidation uye hydroxylation yealkyl, hydroxylation uye oxidation yeammonia, oxidation yesarufa, dealkylation (oxygen, sulfur, ammonia), oxidative dehydrogenation, deamination uye dehalogenation.
Kune 8 mhando dze cytochrome P450 monooxygenase zvigadzirwa (Nhamba seES-CYP-101～ES-CYP-108) yakagadzirwa neSyncoZymes.Nharembozha/Wechat/WhatsApp: +86-13681683526
E-Maillchen@syncozymes.com
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Doro oxidase (AOX)
Pamusoro pedoro oxidase
ES-AOXs: Aya ma enzymes anokwanisa kukonzeresa oxidation yemafuta ane doro kana aryl-doro kuumba aldehydes.Vanoshandisa molecular oxygen asi haidi cofactor yekunze, uye hydrogen peroxide inogadzirwa.
Kune marudzi matanhatu ezvigadzirwa zvedoro oxidase (Nhamba seES-AOX-101~ES-AOX-106) yakagadzirwa neSyncoZymes.ES-AOX101 uye ES-AOX102 vanosarudza aliphatic alcohol substrates, ES-AOX103~ ES-AOX105 vanoda anonhuwirira doro substrates, uye ES-AOX106 ndiyo cholesterol oxidase.SZ-AOX chishandiso chinobatsira kukonzeresa oxidation yemafuta madoro kana aryl-doro kugadzira aldehydes.
Catalytic reaction type:
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E-Maillchen@syncozymes.com
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D-Amino acid dehydrogenase (D-AADH)
Nezve D-Amino acid dehydrogenase
ES-D-AADH (D-Amino acid dehydrogenase): enzyme inogona kuderedza 2-keto acid kuti ienderane neD-amino acid.Kuita kunoda NADP(H) uye inorganic ammonia donor (senge ammonia kana ammonium ion).Kune marudzi gumi nenomwe eD-amino acid dehydrogenases (Nhamba seES-DAADH-101~ ES-DAADH-117) yakagadzirwa neSyncoZymes.
Catalytic reaction type:
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E-Maillchen@syncozymes.com
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Esterase&Lipase (PLE&CALB)
Nezve Esterase&Lipase
ES-PLEs: Kirasi ye hydrolases inokonzeresa kuumbwa uye kutsemuka kwe ester zvisungo.Vanogona kutora chikamu mumhando dzakawanda dzebiochemical reactions, senge esterification, transesterification uye hydrolysis.Iwo anoshandiswa zvakanyanya muminda yakawanda senge kugadzira chikafu, indasitiri yemakemikari, biomedicine, chiral mushonga uye kurapa kwezvakatipoteredza.
Nharembozha/Wechat/WhatsApp: +86-13681683526
E-Maillchen@syncozymes.com
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Epoxide hydrolase (EH)
Nezve epoxide hydrolase
EH is ether hydrolase iyo inokonzera stereoelective hydrolysis ye racemic epoxides kuti ibudise 1, 2-diol uye optical active epoxides, inogona kushandiswa kugadzirisa chiral epoxides kana kugadzirira chiral diols.Vanoshandiswa zvakanyanya mukurapa uye mune mamwe minda.Kune marudzi matatu eepoxide hydrolases zvigadzirwa (Nhamba seES-EH-101～ES-EH-103) yakagadzirwa neSyncoZymes.ES-EH chishandiso chinoshanda chekugadzirisa kuumbwa kwechiral alcohols kuburikidza nestereoelective hydrolysis yealiphatic uye inonhuhwirira epoxides.
Catalytic reaction type:
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E-Maillchen@syncozymes.com
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Formate dehydrogenase (FDH)
Nezve Formate dehydrogenase
ES-FDH (Formate dehydrogenase): FDH inokonzeresa dehydrogenation yeammonium formate kuti ibudise kabhoni dioxide uye ammonia, uye kuderedza NAD kuenda kuNADH neNAD seelectron receptor.FDH inowanzoshandiswa pakuvandudzwa kwecoenzyme NADH.Kune mhando ina dzeFDH enzyme zvigadzirwa (ES-FDH-101~ES-FDH-104) zvakagadziriswa neSyncoZymes, pakati payo ES-FDH102 ine chiitiko chepamusoro uye ndiyo inonyanya kukurudzirwa FDH.
Catalytic reaction type:
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E-Maillchen@syncozymes.com
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Glucose dehydrogenase (GDH)
Pamusoro peGlucose dehydrogenase
ES-GDH (Glucose dehydrogenase): GDH inokonzera dehydrogenation yeglucose kuti ibudise gluconic acid (lactone), uye kuderedza NAD (P) + kuNAD (P) H, neNAD (P) + se electron receptor.GDH inowanzoshandiswa pakuvandudzwa kwecoenzyme NAD (P) H muminda yebiocatalysis ine imwe enzyme huru.Kune marudzi gumi ezvigadzirwa zve enzyme yeGDH (ES-GDH-101~ES-GDH-110) yakagadzirwa neSyncoZymes, pakati payo ES-GDH110 ine chiitiko chepamusoro uye ndiyo inonyanya kukurudzirwa GDH.
Catalytic reaction type:
Nharembozha/Wechat/WhatsApp: +86-13681683526
E-Maillchen@syncozymes.com
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Monoamine oxidase (MAO)
Pamusoro peMonoamine oxidase
ES-MAO (Monoamine oxidase): MAO inokonzeresa iyo oxidative deamination yemonoamines kuburitsa hydrogen peroxide, ammonia uye inoenderana aldehydes.Mukuita kunokonzeresa, okisijeni inodiwa seoxidant.Kune marudzi matanhatu eMAO enzyme zvigadzirwa (Nhamba seES-MAO-101～ES-MAO-106) yakagadziridzwa neSyncoZymes, inogona kushandiswa muoxidative deamination yemonoamine makomponi.
Catalytic reaction type:
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E-Maillchen@syncozymes.com
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Lactate Dehydrogenase (LDH)
Nezve Lactate dehydrogenase
Kune 1 mhando yeLDH enzyme chigadzirwa (Nhamba seES-LDH) yakagadziriswa neSyncoZymes.LDH inogona kukonzera kuderedzwa kwepyruvate kuL-lactic acid, kana kuderedza mamwe akafanana α-keto acids.Mukuita catalysis, NADH inodiwa sehydrogen transporter.
Lactate dehydrogenasecatalytic reaction type
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E-Maillchen@syncozymes.com
