SyncoZymes

zvigadzirwa

  • Ketoreductase (KRED)

    Ketoreductase (KRED)

    Nezve Ketoreductase

    Enzymes: Ari macromolecular biological catalysts, ma enzymes mazhinji mapuroteni.

    Ketoreductase: Iyo inonziwo "Carbonyl reductase", ma enzymes anokonzera kudzokororwa redox reaction pakati pe aldehydes / ketoni nedoro, uye inoda coenzymes seH transmitter seNADH kana NADPH.Kune matatu makuru mapoka eKRED: Short-chain Dehydrogenase / Reductases (SDRs), Medium-chain Dehydrogenases / Reductases (MDRs), uye Aldo-KetoReductases (AKRs).Iwo anokonzeresa mabasa evatatu akafanana, asi chimiro uye zvivakwa zvakasiyana chaizvo.

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  • Transaminase (ATA)

    Transaminase (ATA)

    Nezve transaminase

    ATA kubva SyncoZymes: Kune makumi matanhatu nenhanhatu emhando dzeATA enzyme zvigadzirwa (Nhamba seES-ATA-101~ES-ATA-166) yakagadzirwa neSyncoZymes.SZ-ATA chishandiso chinobatsira chekugadzirisa regio- uye stereoelective synthesis ye chiral amines, amino acids uye zvinobva kune zvakasiyana-siyana zvealiphatic uye anonhuwirira ketoacids, aldehydes, ketoni uye ketose.

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  • Nitrilase (NIT)

    Nitrilase (NIT)

    About Nitrilase

    ES-NITs: Kushandura zvakananga cyanide boka kuita carboxyl boka, kugadzirira carboxylic acid, iyo inoshandiswa zvakanyanya mukurapa, kuchengetedza kwezvakatipoteredza, indasitiri yemakemikari, kuwedzera kwechikafu, machira, kugadzirwa kwekurima uye mamwe minda.
    Kune makumi mana emhando dzeNitrilase(NIT) zvigadzirwa (Nhamba seES-NIT-101~ES-NIT-140) yakagadzirwa neSyncoZymes.ES-NIT chishandiso chinobatsira kukonzeresa kuumbwa kwechiral carboxylic acids kuburikidza neregio- uye stereoelective hydrolysis yeakasiyana-siyana aliphatic uye anonhuwirira nitriles.

    Catalytic reaction type:

    Nitrilase NIT2

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  • Nitrile hydratase (NHT)

    Nitrile hydratase (NHT)

    Pamusoro peES-NHTs

    ES-NHTs: kirasi yemetalloenzyme, iyo inosarudza hydrate nitriles mune inoenderana yekutanga amide.Izvo zvakanyanya kushandiswa kwete chete pakugadzirwa kweamino acids, amides, carboxylic acids uye zvinobva kwavari, asiwo pakugadzira chiral zvinodhaka.Kune makumi maviri nemana marudzi e nitrile hydratases akagadzirwa ne SyncoZymes (Nhamba se ES-NHT-101~ES-NHT-124).
    Catalytic reaction type:

    Nitrile hydratase NHT2

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    E-Maillchen@syncozymes.com

  • Amidase (AMD)

    Amidase (AMD)

    AMD kubva SyncoZymes: Kune gumi nemapfumbamwe marudzi eAMD enzyme zvigadzirwa (Nhamba seES-AMD-101~ES-AMD-119) yakagadziriswa neSyncoZymes.SZ-AMD chishandiso chinobatsira chekugadzirisa regio- uye stereoelective synthesis ye chiral carboxylic acids uye zvinobva kune zvakasiyana-siyana zvealiphatic uye anonhuwirira amides.

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  • Ene reductase (ERED)

    Ene reductase (ERED)

    About ene reductase

    ES-EREDs: Ndevemhuri yekare yero enzymes iyo inosarudza kuderedza C = C mu α, β -unsaturated compounds nemapoka e-electron-absorbing.Iwo anoshandiswa zvakanyanya mukudzidza kweamino acid derivatives, bioactive substances, pharmaceutical intermediates, zvinonhuwira uye chiral blocks.

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  • Oxynitrilases (HNL)

    Oxynitrilases (HNL)

    Nezve oxynitrilases

    ES-HNLs: Enzyme yekirasi iyo inantioselectively inokonzeresa kuwedzera kweHCN kune aldehydes (ketones) kuwana R kana S mhando cyanide alcohols, inogona kushandurwa nyore nyore kuva marudzi mazhinji emishonga kana zvinodhaka zvepakati kuburikidza nemakemikari nzira.
    Kune makumi maviri nepfumbamwe emhando dzezvigadzirwa zve oxynitrilase (Nhamba seES-HNL-101~ES-HNL-129) yakagadzirwa neSyncoZymes.SZ-HNL chishandiso chinobatsira kune regio- uye stereo- selective synthesis ye (R) -cyanohydrins kana (S) -cyanohydrins kubva kune zvakasiyana-siyana zvinonhuhwirira, aliphatic uye heterocyclic aldehydes kana kunyange ketoni.
    Catalytic reaction type:

    Oxynitrilases HNL2

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  • Nitro reductase (NTR)

    Nitro reductase (NTR)

    Nezve nitro reductase

    ES-NTRs: Maflavoenzymes anokonzera kuderedzwa kweNAD (P) H-inotsamira kwemapoka e nitro pane nitroaromatic uye nitroheterocyclic makomisheni kune hydroxylamino uye/kana amino derivatives.Iwo anoshandiswa zvakanyanya muorganic synthesis yeanonhuwirira hydroxylamine uye anonhuwirira amine, bundu kurapa, kucherechedzwa kwebiological uye kushatisa kwezvakatipoteredza zvinosvibisa.Kune marudzi gumi nemaviri eNitro reductase (NTR) zvigadzirwa (Nhamba seES-NTR-101~ES-NTR-112) yakagadzirwa neSyncoZymes.

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  • Aldolase (DERA)

    Aldolase (DERA)

    ES-DERAs: Inogona kunyatso gadzirisa iyo stereoselective yekuwedzera yevanopa ketoni kune receptor aldehydes.Uyezve, maitiro anogona kuitwa mune aqueous solution yearere pH pasina akakosha ekudzivirira matanho.Ivo ndevekirasi I aldolase, iyo inoumba Shiff base mune inokonzeresa maitiro.Iyo substrate inosungirirwa zvakabatana neboka reamino renzvimbo inoshanda kuti itange kuparara uye kuumbwa kwechisungo.Musiyano uripo pakati peDERA nemamwe maaldolases ndewekuti masubstrates avanokonzeresa maaldehydes uye anogona kuenderera mberi aldehydes condensation.

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  • Cytochrome P450 monooxygenase (CYP)

    Cytochrome P450 monooxygenase (CYP)

    Nezve CYP

    ES-CYPs: Kirasi redox enzymes ine mercaptan-heme senzvimbo inoshanda yekukonzeresa kutamisa okisijeni.Iwo materminal oxygenases uye anoda heme kuti aite okisijeni.

    Cytochrome P450 monooxygenase catalyze the oxidation, epoxidation uye hydroxylation yealkyl, hydroxylation uye oxidation yeammonia, oxidation yesarufa, dealkylation (oxygen, sulfur, ammonia), oxidative dehydrogenation, deamination uye dehalogenation.
    Kune 8 mhando dze cytochrome P450 monooxygenase zvigadzirwa (Nhamba seES-CYP-101~ES-CYP-108) yakagadzirwa neSyncoZymes.

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    E-Maillchen@syncozymes.com

  • Doro oxidase (AOX)

    Doro oxidase (AOX)

    Pamusoro pedoro oxidase

    ES-AOXs: Aya ma enzymes anokwanisa kukonzeresa oxidation yemafuta ane doro kana aryl-doro kuumba aldehydes.Vanoshandisa molecular oxygen asi haidi cofactor yekunze, uye hydrogen peroxide inogadzirwa.

    Kune marudzi matanhatu ezvigadzirwa zvedoro oxidase (Nhamba seES-AOX-101~ES-AOX-106) yakagadzirwa neSyncoZymes.ES-AOX101 uye ES-AOX102 vanosarudza aliphatic alcohol substrates, ES-AOX103~ ES-AOX105 vanoda anonhuwirira doro substrates, uye ES-AOX106 ndiyo cholesterol oxidase.SZ-AOX chishandiso chinobatsira kukonzeresa oxidation yemafuta madoro kana aryl-doro kugadzira aldehydes.

    Catalytic reaction type:

    AOX

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  • D-Amino acid dehydrogenase (D-AADH)

    D-Amino acid dehydrogenase (D-AADH)

    Nezve D-Amino acid dehydrogenase

    ES-D-AADH (D-Amino acid dehydrogenase): enzyme inogona kuderedza 2-keto acid kuti ienderane neD-amino acid.Kuita kunoda NADP(H) uye inorganic ammonia donor (senge ammonia kana ammonium ion).Kune marudzi gumi nenomwe eD-amino acid dehydrogenases (Nhamba seES-DAADH-101~ ES-DAADH-117) yakagadzirwa neSyncoZymes.

    Catalytic reaction type:

    D-amino acid dehydrogenase2

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    E-Maillchen@syncozymes.com